Research Areas

Who are we?

Protein Folding

Protein Folding

Predicting Folding Dynamics

Predicting Folding Dynamics

Photoswitchable allosteric proteins

Photoswitchable allosteric proteins

Membrane Proteins

Membrane Proteins

Psi analysis

Psi analysis

Conformational Entropy

Conformational Entropy

M.C. Baxa, X. Lin, C.D. Mukinay, S. Chakravarthy, J.R. Sacheleben, S. Antilla, N. Hartrampf, J.A. Riback, I.A. Gagnon, B.L. Pentelute, P.L. Clark, T.R. Sosnick, "How hydrophobicity, side chains, and salt affect the dimensions of disordered proteins" Prot Sci 33(5):e4986 (2024).

H. Glauninger, J.A.M. Bard, C.W. Hickernell, E.M. Airoldi, W. Li, R.H. Singer, S. Paul, J. Fei, T.R. Sosnick, E.W.J. Wallace, D.A. Drummond, "Transcriptome-wide mRNA condensation precedes stress granule formation and excludes stress-induced transcripts" bioRxiv 2024.04.15.589678

S.K. Kik, D. Christopher, H. Glauninger, C.W. Hickernell, J.A.M. Bard, M. Ford, T.R. Sosnick, D.A. Drummond, "An adaptive biomolecular condensation response is conserved across environmentally divergent species" Nat Comm 15, 3127 (2024).

X. Lin, P. Haller, N. Bavi, N. Faruk, E. Perozo, T.R. Sosnick, "Folding of Prestin’s Anion-Binding Site and the Mechanism of Outer Hair Cell Electromotility" eLife 12:RP89635

University of Chicago
Biochemistry & Molecular Biophsyics
Biophysical Sciences
Institute for Molecular Engineering
Institute for Biophysical Dynamics
UChicago
NSF Graduate Research Fellowship
NIH