Research Areas

Who are we?

Protein Folding

Protein Folding

Predicting Folding Dynamics

Predicting Folding Dynamics

Photoswitchable allosteric proteins

Photoswitchable allosteric proteins

Membrane Proteins

Membrane Proteins

Psi analysis

Psi analysis

Conformational Entropy

Conformational Entropy

J.A. Riback*, C.D. Katanski*, J.L. Kear-Scott, E.V. Pilipenko, A.E. Rojek, T.R. Sosnick, D.A. Drummond, "Stress-Triggered Phase Separation Is an Adaptive, Evolutionarily Tuned Response" Cell 168 (2017) 1028-40.

A.R. French, T.R. Sosnick, R.S. Rock, "Investigations of human myosin VI targeting using optogenetically controlled cargo loading" Proc Natl Acad Sci U S A 114 (2017) E1607-16.

Z.P. Gates*, M.C. Baxa*, W. Yu, J.A. Riback, H. Li, B. Roux, S.B.H. Kent, T.R. Sosnick, "Perplexing cooperative folding and stability of a low-sequence complexity, polyproline 2 protein lacking a hydrophobic core" Proc Natl Acad Sci U S A 114 (2017) 2241-6.

B. Basanta, K.K. Chan, P. Barth, T. King, T.R. Sosnick, J.R. Hinshaw, G. Liu, J.K. Everett, R. Xiao, G.T. Montelione, D. Baker, "Introduction of a polar core into the de novo designed protein Top7" Protein Sci 25 (2016) 1299-307.

University of Chicago
Biochemistry & Molecular Biophsyics
Biophysical Sciences
Institute for Molecular Engineering
Institute for Biophysical Dynamics
UChicago
NSF Graduate Research Fellowship
NIH