Research Areas in The Sosnick Group at The University of Chicago
Recent Publications
X. Lin*,A.V. Molina*, J. Shangguan*, R. Chen, T.R. Sosnick, "Practical Tips for the Application of HDX-MS to Membrane Proteins, Biomolecular Condensates, and Weak Protein Binders" J. Am. Soc. Mass Spectrom. 36, 1575-87 (2025)
T.R. Sosnick, M.C. Baxa, "Collapse and Protein Folding: Should We Be Surprised That Biothermodynamics Works So Well?" Annu. Rev. Biophys 54, 17-45 (2025)
J.M. Mancl, W.G. Liang, N.L. Bayhi, H. Wei, W. Budell, J.H. Mendez, T.R. Sosnick, B. Carragher, C.S. Potter, W.J. Tang, "Characterization and modulation of human insulin degrading enzyme conformational dynamics to control enzyme activity" bioRxiv 2024.12.30.630732
K.L. Kroll, T.R. Sosnick, R.S. Rock, "Design and Use of AsLOV2-Based Optogenetic Tools for Actin Imaging. " Baumschlager, A. (eds) Optogenetics. Methods in Molecular Biology, vol 2840 (2025) 89-100.
N. Zhang, D. Sood, S.C. Guo, N. Chen, A. Antoszewski, T. Marianchuk, S. Dey, Y. Xiao, L. Hong, X. Peng, M.C. Baxa, C. Partch, L.P. Wang, T.R. Sosnick, A.R. Dinner, A. LiWang, "Temperature-dependent fold-switching mechanism of the circadian clock protein KaiB" Proc Natl Acad Sci U S A 121 (2024) e2412327121.
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