Josiah Zayner

Currently I spend much of my time studying the biophysical properties of the LOV2 domain from Avena sativa. I enjoy NMR and CD spectroscopy and generally like to tear apart proteins to see how they work. I also do MD simulation stuff. Generally, I try to make sure I have access to a wide variety of tools as a scientist to help me solve problems.
In my previous life I did a lot of computer programming and still enjoy hacking hardware and software. Here are some links to some of the code I have written and stuff I have built.

The Adams Lab had a broken pH meter. The connections between the buttons and the microprocessors were crap and died. I did a little reverse engineering and rebuilt a keypad using an old computer keyboard and some button press switches.

I made an accelerometer based mouse glove for linux. It uses an arduino as the analog interface. I used perl to poll the USB interface and move the mouse. There is a pressure sensor attached to the thumb that can left or right click based on the amount of pressure you use. Click here to watch the video

IP Sorcery : a packet generator with a GUI interface very easy to mess around with and learn about firewalls and network protocols. It is used mostly for testing firewall rules and network troubleshooting.

Quick Changer is a perl script I wrote that allows one to generate quick change primers to mutate a single residue. All one needs to do is give the program a text file contaning the sequence, the residue number to mutate and what to mutate it to.

For performing simulations to test the viscosity of certain whiskeys I created a 40% ethanol/water box. The files were created for use with OPLSAA forcefield for use in gromacs.

Energy minimized Ethanol Box using the SPC model for water

Scripts and stuff for MD simulations and NMR